Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 11/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5575257 | 0.98 | FDPS (0.47) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL8016903 | 0.98 | FDPS (0.47) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL2810471 | 0.98 | FDPS (0.47) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL5575514 | 0.98 | FDPS (0.47) | FDPSGGPS1SMPD1CES2 | |
| Ethylene SCHEMBL933388 | 0.94 | FDPS (0.44) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL9282122 | 0.93 | FDPS (0.41) | FDPSGGPS1CES2 | |
| Cyclohexane SCHEMBL1967354 | 0.92 | FDPS (0.42) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL9860581 | 0.90 | DNM1 (0.50) | FDPSSMPD1 | |
| Octadecanoic Acid Amide SCHEMBL28078346 | 0.87 | SOAT1 (0.50) | FDPSGGPS1SMPD1CES2 | |
| SCHEMBL7190941 | 0.87 | FAAH (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064275-A1 | PROCESS FOR PRODUCING SIMVASTATIN AND/OR ITS DERIVATIVES | Synthon B.V. (NL) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999045003-A1 | PROCESS FOR PRODUCING SIMVASTATIN AND/OR ITS DERIVATIVES | SYNTHON B.V. (NL) | 1999-09-10 | — | — | WO | disclosed |