Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TKT | P29401 | 5/20 | 0.59 |
| ▸ | PPP5C | P53041 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL459651 | 0.88 | LMNA (0.66) | LMNATKTPPP5CTDP1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL15320267 | 0.88 | LMNA (0.65) | LMNATKTPPP5CTDP1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL1533810 | 0.87 | PPP5C (0.67) | LMNATKTPPP5CTDP1HSP90AA1 | |
| SCHEMBL30249786 | 0.86 | LMNA (0.66) | LMNATKTPPP5CTDP1HSP90AA1 | |
| SCHEMBL2512165 | 0.86 | PPP5C (0.68) | LMNATKTPPP5CTDP1HSP90AA1 | |
| SCHEMBL31477791 | 0.84 | PPP5C (0.70) | LMNATKTPPP5CTDP1HSP90AA1 | |
| Hydrochloric Acid SCHEMBL3908684 | 0.83 | PPP5C (0.64) | LMNATKTPPP5CTDP1HSP90AA1 | |
| Cocarboxylase SCHEMBL8923435 | 0.81 | LMNA (0.98) | LMNATKTPPP5CTDP1HSP90AA1 | |
| Cocarboxylase SCHEMBL21111 | 0.81 | LMNA (0.98) | LMNATKTPPP5CTDP1HSP90AA1 | |
| Phosphoric Acid SCHEMBL991151 | 0.81 | LMNA (0.93) | LMNATKTPPP5CTDP1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130196359-A1 | SYSTEMS AND METHODS FOR BIOTRANSFORMATION OF CARBON DIOXIDE INTO HIGHER CARBON COMPOUNDS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2013-08-01 | — | — | US | claimed |
| WO-2012037413-A2 | SYSTEMS AND METHODS FOR BIOTRANSFORMATION OF CARBON DIOXIDE INTO HIGHER CARBON COMPOUNDS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2012-03-22 | — | — | WO | claimed |
| US-9023627-B2 | Systems and methods for biotransformation of carbon dioxide into higher carbon compounds | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2015-05-05 | — | — | US | disclosed |
| US-20130196359-A1 | SYSTEMS AND METHODS FOR BIOTRANSFORMATION OF CARBON DIOXIDE INTO HIGHER CARBON COMPOUNDS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2013-08-01 | — | — | US | disclosed |
| WO-2012037413-A2 | SYSTEMS AND METHODS FOR BIOTRANSFORMATION OF CARBON DIOXIDE INTO HIGHER CARBON COMPOUNDS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2012-03-22 | — | — | WO | disclosed |