Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 3/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12786875 | 0.85 | FBP1 (0.59) | KAT2BFBP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL7872540 | 0.84 | AKR1C3 (0.53) | FBP1L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL28853179 | 0.84 | TDP1 (0.62) | KAT2BBPTFL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL2330493 | 0.81 | L3MBTL1 (0.65) | KAT2BFBP1CYP3A4TSHRL3MBTL1 | |
| SCHEMBL7880687 | 0.78 | BRD4 (0.43) | BPTFL3MBTL1TDP1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL7876724 | 0.77 | BRD4 (0.43) | BPTFL3MBTL1TDP1ALDH1A1MAPT | |
| SCHEMBL2327163 | 0.75 | L3MBTL1 (0.56) | KAT2BFBP1TSHRL3MBTL1TDP1 | |
| SCHEMBL14247885 | 0.75 | FBP1 (0.55) | FBP1CYP3A4TSHRL3MBTL1TDP1 | |
| SCHEMBL4940284 | 0.74 | TDP1 (0.68) | FBP1L3MBTL1TDP1ALDH1A1MAPK1 | |
| SCHEMBL16767959 | 0.74 | L3MBTL1 (0.60) | KAT2BFBP1CYP3A4TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1244542-C | Aromatic amine derivatives having NOS inhibitory effect | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2006-03-08 | — | — | CN | claimed |
| US-6331553-B1 | INHIBITORS OF NITRIC OXIDE SYNTHASE; TREATING CEREBROVASCULAR DISEASES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-12-18 | — | — | US | claimed |
| CN-1240419-A | Aromatic amine derivatives having NOS inhibitory effect | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-01-05 | — | — | CN | claimed |
| EP-0949242-A1 | AROMATIC AMINE DERIVATIVES HAVING NOS INHIBITORY EFFECT | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-10-13 | — | — | EP | claimed |
| CN-1244542-C | Aromatic amine derivatives having NOS inhibitory effect | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2006-03-08 | — | — | CN | disclosed |
| US-6331553-B1 | INHIBITORS OF NITRIC OXIDE SYNTHASE; TREATING CEREBROVASCULAR DISEASES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-12-18 | — | — | US | disclosed |
| CN-1240419-A | Aromatic amine derivatives having NOS inhibitory effect | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2000-01-05 | — | — | CN | disclosed |
| EP-0949242-A1 | AROMATIC AMINE DERIVATIVES HAVING NOS INHIBITORY EFFECT | Chugai Seiyaku Kabushiki Kaisha (JP) | 1999-10-13 | — | — | EP | disclosed |