Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 4/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.49 |
| ▸ | KDR | P35968 | 10/20 | 0.49 |
| ▸ | BRAF | P15056 | 3/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679527 | 0.93 | KDR (0.49) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL7791086 | 0.92 | KDR (0.49) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL679617 | 0.92 | RAF1 (0.45) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL7776445 | 0.91 | RAF1 (0.46) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL8683809 | 0.89 | KDR (0.48) | RAF1MAPK3KDRBRAF | |
| SCHEMBL8773801 | 0.86 | KDR (0.47) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL679549 | 0.86 | RAF1 (0.43) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL6938479 | 0.82 | KDR (0.48) | KDRBRAFKMOPLA2G7 | |
| SCHEMBL15195551 | 0.81 | KDM4E (0.47) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL8199428 | 0.79 | KDR (0.44) | RAF1MAPK3KDRBRAFPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650482-B1 | PESTICIDAL PYRIMIDINE COMPOUNDS | BASF AG (DE) | 2001-10-04 | — | — | EP | disclosed |
| US-5707995-A | APPLYING TO SKINS/COATS OF ANIMALS TO CONTROL TICKS, INSECTS, PARASITES | AMERICAN CYANAMID COMPANY (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0650482-A1 | PESTICIDAL PYRIMIDINE COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994002470-A1 | PESTICIDAL PYRIMIDINE COMPOUNDS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1994-02-03 | — | — | WO | disclosed |