Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 4/20 | 0.45 |
| ▸ | MAPK3 | P27361 | 4/20 | 0.45 |
| ▸ | KDR | P35968 | 10/20 | 0.44 |
| ▸ | BRAF | P15056 | 3/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7885604 | 0.92 | RAF1 (0.49) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL679527 | 0.85 | KDR (0.49) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL7791086 | 0.85 | KDR (0.49) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL7776445 | 0.83 | RAF1 (0.46) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL8683809 | 0.82 | KDR (0.48) | RAF1MAPK3KDRBRAF | |
| SCHEMBL8773801 | 0.79 | KDR (0.47) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL679549 | 0.79 | RAF1 (0.43) | RAF1MAPK3KDRBRAFKMO | |
| SCHEMBL6938479 | 0.75 | KDR (0.48) | KDRBRAFKMOPLA2G7 | |
| SCHEMBL15195551 | 0.74 | KDM4E (0.47) | RAF1MAPK3KDRBRAFPLA2G7 | |
| SCHEMBL1201822 | 0.74 | KDM4E (0.50) | RAF1MAPK3KDRBRAFPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1982594-B1 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-05-14 | — | — | EP | claimed |
| JP-4754495-B2 | — | — | 2011-08-24 | — | — | JP | claimed |
| US-20100204167-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2010-08-12 | — | — | US | claimed |
| US-20100197737-A1 | ACTIVE AGENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | US | claimed |
| EP-1982594-A1 | Active agent combinations with insecticidal and acaricidal properties | Bayer CropScience AG (DE) | 2008-10-22 | — | — | EP | claimed |
| US-20080027114-A1 | Active Agent Combinations with Insecticidal and Acaricidal Properties | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2008-01-31 | — | — | US | claimed |
| EP-1686858-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES | Bayer CropScience AG (DE) | 2006-08-09 | — | — | EP | claimed |
| WO-2005048712-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-02 | — | — | WO | claimed |
| US-9173394-B2 | Active agent combinations having insecticidal and acaricidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-11-03 | — | — | US | disclosed |
| US-8962672-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2015-02-24 | — | — | US | disclosed |
| EP-1982594-B1 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2014-05-14 | — | — | EP | disclosed |
| US-8299036-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2012-10-30 | — | — | US | disclosed |
| US-20120010076-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | US | disclosed |
| US-8044085-B2 | Active agent combinations with insecticidal and acaricidal properties | BAYER CROPSCIENCE AG (DE) | 2011-10-25 | — | — | US | disclosed |
| EP-1686858-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES | Bayer CropScience AG (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005048712-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERTIES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-06-02 | — | — | WO | disclosed |
| US-20040186171-A1 | Combinations of active ingredients with insecticidal and acaricidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-09-23 | — | — | US | disclosed |
| US-6706758-B2 | SYNERGISTIC DIHYDROFURANONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-03-16 | — | — | US | disclosed |
| US-20040023959-A1 | Active agent combinations with insecticidal and acaricidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-02-05 | — | — | US | disclosed |
| US-20030114312-A1 | Combinations of active ingredients with insecticidal and acaricidal properties | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114312-A1 | Combinations of active ingredients with insecticidal and acaricidal properties | ACAA2, AADAC, ACACA | RAF1 3554/4885MAPK3 3527/4885KDR 4806/4885 |
| US-20100197737-A1 | ACTIVE AGENT COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | ACHE, AADAC, AMY1A | RAF1 3886/4885MAPK3 4425/4885KDR 4715/4885 |
| US-20080027114-A1 | Active Agent Combinations with Insecticidal and Acaricidal Properties | AADAC, ACAA2, AAAS | RAF1 3003/4885MAPK3 1756/4885KDR 4717/4885 |
| US-20040023959-A1 | Active agent combinations with insecticidal and acaricidal properties | ACAA2, AADAC, ACHE | RAF1 3517/4885MAPK3 3361/4885KDR 4746/4885 |
| US-20120010076-A1 | ACTIVE AGENT COMBINATIONS WITH INSECTICIDAL AND ACARICIDAL PROPERITIES | ACAA2, ACHE, AADAC | RAF1 3027/4885MAPK3 2527/4885KDR 4766/4885 |
| US-20040186171-A1 | Combinations of active ingredients with insecticidal and acaricidal properties | AADAC, CYP51A1, ACAA2 | RAF1 3742/4885MAPK3 3108/4885KDR 4802/4885 |
| US-20100204167-A1 | ACTIVE COMPOUND COMBINATIONS HAVING INSECTICIDAL AND ACARICIDAL PROPERTIES | ACHE, ACAT2, ACAT1 | RAF1 4283/4885MAPK3 4272/4885KDR 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.