Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28188740 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1TDP1ADORA2AADORA1PLA2G7 | |
| Icodulinum SCHEMBL380085 | 0.81 | NPC1 (0.47) | ALDH1A1TDP1PLA2G7SMN1; SMN2NPC1 | |
| Icodulinum SCHEMBL2746827 | 0.80 | NPC1 (0.46) | ALDH1A1TDP1PLA2G7SMN1; SMN2NPC1 | |
| SCHEMBL11588150 | 0.74 | AKR1C3 (0.47) | ADORA2AADORA1SCN5ALMNAMEN1 | |
| SCHEMBL19998626 | 0.73 | KDM4E (0.45) | ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11588086 | 0.73 | PKM (0.45) | ALDH1A1ADORA2AADORA1SCN5ALMNA | |
| SCHEMBL5762561 | 0.73 | PLA2G7 (0.58) | ALDH1A1PLA2G7SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12121115 | 0.73 | NPC1 (0.62) | ALDH1A1ADORA2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL2066178 | 0.72 | KMT2A (0.52) | ALDH1A1TDP1PLA2G7SMN1; SMN2NPC1 | |
| SCHEMBL16657376 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TDP1PLA2G7SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | claimed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | claimed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | claimed |
| US-7737159-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2010-06-15 | — | — | US | disclosed |
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | ABBVIE INC. | 2007-06-21 | — | — | US | disclosed |
| US-7196200-B2 | Antibacterial compounds | ABBOTT LABORATORIES (US) | 2007-03-27 | — | — | US | disclosed |
| US-20050159423-A1 | Antibacterial compounds | ABBOTT LABORATORIES | 2005-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142353-A1 | ANTIBACTERIAL COMPOUNDS | MRPL21, FDPS, PGLS | ALDH1A1 2936/4885TDP1 3345/4885ADORA2A 4407/4885 |
| US-20050159423-A1 | Antibacterial compounds | MRPL21, FDPS, PGLS | ALDH1A1 2936/4885TDP1 3345/4885ADORA2A 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.