SCHEMBL788568

SCHEMBL788568

CC1(C)c2ccccc2-c2ccc(-c3ccc4oc5c(-c6ccc7[nH]c8ccc(-c9cc(-c%10ccc%11c(c%10)C(C)(C)c%10ccccc%10-%11)cc%10c9oc9ccc(-c%11ccc%12c(c%11)C(C)(C)c%11ccccc%11-%12)cc9%10)cc8c7c6)cc(-c6ccc7c(c6)C(C)(C)c6ccccc6-7)cc5c4c3)cc21

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
CASP3 P42574 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788711 0.97 ALOX5 (0.33) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL788770 0.87 ALOX5 (0.47) ALOX5CASP3SENP7SENP6
SCHEMBL10226914 0.83 ALOX5 (0.38) ALOX5
SCHEMBL8281495 0.83 ALDH1A1 (0.36) CASP3SENP7SENP6
SCHEMBL4549408 0.82 ALOX5 (0.32) ALOX5
SCHEMBL1636359 0.81 ALOX5 (0.36) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL10226002 0.81 GAA (0.42) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL10227111 0.81 GAA (0.42) ALOX5PIM1CSNK2A2CSNK2BPIM3
SCHEMBL787366 0.81 ALOX5 (0.36) ALOX5
SCHEMBL8281415 0.81 HPGD (0.39) PIM1CSNK2A2CSNK2BPIM3PIM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PIM1 3603/4885CSNK2A2 1485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.