Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7890873 | 0.88 | PTPN1 (0.47) | ACKR3PTPN1MEN1KMT2AMAPT | |
| SCHEMBL7886936 | 0.87 | PTPN1 (0.48) | ACKR3PTPN1MEN1KMT2AMAPT | |
| SCHEMBL7880879 | 0.83 | NCEH1 (0.48) | ALDH1A1CYP2C19CYP2D6CYP2C9CYP1A2 | |
| SCHEMBL8211512 | 0.81 | ACKR3 (0.55) | ACKR3PTPN1MEN1KMT2AMAPT | |
| SCHEMBL7893101 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AMAPTALDH1A1CYP2C19 | |
| SCHEMBL7889273 | 0.76 | FAAH (0.48) | KMT2AMAPTALDH1A1 | |
| SCHEMBL7426581 | 0.76 | TSHR (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3275588 | 0.76 | ACKR3 (0.59) | ACKR3PTPN1MEN1KMT2AALDH1A1 | |
| SCHEMBL7890923 | 0.75 | PTPN1 (0.44) | ACKR3PTPN1MEN1KMT2AMAPT | |
| SCHEMBL4582840 | 0.73 | PTPN1 (0.63) | ACKR3PTPN1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934301-B1 | AMINOTHIOPHENE CARBOXYLIC ACID AMIDES AND THE USE THEREOF AS PHOSPHODIESTERASE INHIBITORS | MERCK PATENT GMBH (DE) | 2001-06-20 | — | — | EP | disclosed |