Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.43 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7880879 | 0.87 | NCEH1 (0.48) | FAAHTP53TSHRCHRM4ALDH1A1 | |
| SCHEMBL7888358 | 0.85 | FAAH (0.49) | FAAHKCNQ3KCNQ2KCNQ4KCNQ5 | |
| SCHEMBL7420200 | 0.85 | FAAH (0.48) | FAAHNPSR1LMNAKDM4ETP53 | |
| SCHEMBL7893101 | 0.83 | ALDH1A1 (0.56) | KMT2ALMNATSHRALDH1A1MAPT | |
| SCHEMBL7426581 | 0.80 | TSHR (0.49) | KMT2ALMNATSHRALDH1A1HPGD | |
| SCHEMBL7423152 | 0.79 | SMN1; SMN2 (0.61) | KMT2ALMNAKDM4ECHRM4ALDH1A1 | |
| SCHEMBL8207487 | 0.78 | KMT2A (0.51) | KMT2ALMNAKDM4ETSHRCHRM4 | |
| SCHEMBL7888367 | 0.76 | ACKR3 (0.47) | KMT2AALDH1A1MAPT | |
| SCHEMBL21051218 | 0.74 | FAAH (0.52) | FAAHKCNQ3KCNQ2KMT2ALMNA | |
| SCHEMBL7886963 | 0.72 | NPC1 (0.47) | FAAHKMT2AALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934301-B1 | AMINOTHIOPHENE CARBOXYLIC ACID AMIDES AND THE USE THEREOF AS PHOSPHODIESTERASE INHIBITORS | MERCK PATENT GMBH (DE) | 2001-06-20 | — | — | EP | disclosed |