Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CD69 | Q07108 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29556423 | 1.00 | ALDH1A1 (0.52) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL7154639 | 1.00 | ALDH1A1 (0.52) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL7154645 | 1.00 | ALDH1A1 (0.52) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL16373481 | 0.89 | LGALS8 (0.45) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL6324514 | 0.88 | LMNA (0.53) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL6324521 | 0.88 | LMNA (0.53) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL10687435 | 0.88 | LMNA (0.53) | ALDH1A1THRBMAPK1CD69LGALS8 | |
| SCHEMBL7155543 | 0.88 | ALDH1A1 (0.65) | ALDH1A1THRBMAPK1CD69KMT2A | |
| SCHEMBL7155546 | 0.88 | ALDH1A1 (0.65) | ALDH1A1THRBMAPK1CD69KMT2A | |
| SCHEMBL5177597 | 0.87 | LMNA (0.54) | ALDH1A1THRBMAPK1CD69LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711766-B1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN IND LTD (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5627290-A | 2,3-didehydrosialic acid substituted with fluorine at 7-position and synthetic intermediate thereof | DAIKIN INDUSTRIES, LTD. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0711766-A1 | 7-FLUORO-2, 3-DIDEHYDROSIALIC ACID AND INTERMEDIATE FOR SYNTHESIS THEREOF | DAIKIN INDUSTRIES, LIMITED (JP) | 1996-05-15 | — | — | EP | disclosed |