Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.54 |
| ▸ | NPC1 | O15118 | 11/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | MLYCD | O95822 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207961 | 0.90 | MGLL (0.53) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7888341 | 0.88 | NR1H4 (0.50) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7888439 | 0.87 | GRIN2C (0.57) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7888363 | 0.86 | RAB9A (0.51) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8210714 | 0.79 | KDM4E (0.51) | MAPTALDH1A1LMNAHPGDHTT | |
| SCHEMBL7888441 | 0.79 | PTGER4 (0.53) | LMNA | |
| SCHEMBL7890928 | 0.78 | NPC1 (0.47) | RAB9ANPC1MAPTHTTCNR1 | |
| SCHEMBL8199930 | 0.78 | MGLL (0.52) | RAB9ANPC1HDAC2HDAC8HDAC6 | |
| Bicarbonate SCHEMBL7890931 | 0.78 | SMN1; SMN2 (0.51) | RAB9ANPC1ALDH1A1LMNAHPGD | |
| SCHEMBL8208065 | 0.78 | MAPT (0.53) | RAB9ANPC1MAPTNPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934301-B1 | AMINOTHIOPHENE CARBOXYLIC ACID AMIDES AND THE USE THEREOF AS PHOSPHODIESTERASE INHIBITORS | MERCK PATENT GMBH (DE) | 2001-06-20 | — | — | EP | disclosed |
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |