Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11267018 | 0.88 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TSHRCA12CA9 | |
| SCHEMBL7896003 | 0.78 | ALDH1A1 (0.60) | ALDH1A1TSHRCA12CA9CA2 | |
| SCHEMBL11705310 | 0.76 | CYP11B1 (0.56) | ALDH1A1POLB | |
| SCHEMBL2783969 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TSHRCA12CA9 | |
| SCHEMBL7114927 | 0.75 | ACHE (0.56) | SMN1; SMN2ALDH1A1TSHRCA12CA9 | |
| SCHEMBL12511057 | 0.74 | ACHE (0.74) | SMN1; SMN2ALDH1A1TSHRACHEHTT | |
| SCHEMBL3202573 | 0.73 | ALDH1A1 (0.72) | ALDH1A1TSHRACHEHTTHPGD | |
| SCHEMBL28663777 | 0.73 | GSK3B (0.53) | ALDH1A1TSHRCA12CA9CA2 | |
| SCHEMBL4047966 | 0.73 | TYR (0.67) | ALDH1A1TSHRCA12CA9CA2 | |
| SCHEMBL21634376 | 0.73 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1TSHRCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6183934-B1 | FOE USE IN FORMATION OF PATTERN OF INSULATION FILM, PASSIVATION FILM, .ALPHA.-RAY SHIELDING FILM, OPTICAL WAVEGUIDE | KABUSHIKI KAISHA TOSHIBA (JP) | 2001-02-06 | — | — | US | disclosed |