SCHEMBL11267018

SCHEMBL11267018

O=[N+]([O-])c1ccccc1Cn1cccc1

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
TSHR P16473 1/20 0.56
ACHE P22303 2/20 0.53
HPGD P15428 1/20 0.51
GAA P10253 1/20 0.50
CA12 O43570 2/20 0.49
CA9 Q16790 2/20 0.49
MEN1 O00255 1/20 0.49
POLB P06746 1/20 0.49
KMT2A Q03164 1/20 0.49
CA2 P00918 1/20 0.49
KDM4E B2RXH2 1/20 0.49
HTT P42858 2/20 0.48
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
AR P10275 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7889115 0.88 SMN1; SMN2 (0.56) ALDH1A1TSHRACHEHPGDGAA
SCHEMBL11705310 0.80 CYP11B1 (0.56) ALDH1A1POLB
SCHEMBL6054861 0.78 ALDH1A1 (0.50) ALDH1A1TSHRACHEHPGDGAA
SCHEMBL11255408 0.78 MEN1 (0.47) ALDH1A1TSHRHPGDGAAMEN1
SCHEMBL12511057 0.78 ACHE (0.74) ALDH1A1TSHRACHEMEN1POLB
SCHEMBL3202573 0.78 ALDH1A1 (0.72) ALDH1A1TSHRACHEHPGDMEN1
SCHEMBL1696805 0.76 ALDH1A1 (0.64) ALDH1A1TSHRACHEHPGDMEN1
SCHEMBL301933 0.76 ALDH1A1 (0.69) ALDH1A1TSHRACHEHPGDMEN1
SCHEMBL27848284 0.76 ALDH1A1 (0.58) ALDH1A1TSHRACHEHPGDGAA
SCHEMBL7114927 0.75 ACHE (0.56) ALDH1A1TSHRACHEHPGDCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102569896-B Lithium ion secondary battery and preparation method thereof BYD CO LTD 2015-01-14 CN disclosed
CN-102569896-A Lithium ion secondary battery and preparation method thereof BYD CO LTD 2012-07-11 CN disclosed
CN-1889955-A Tricyclic imidazopyridines for use as gastric secretion inhibitors ALTANA PHARMA AG (DE) 2007-01-03 CN disclosed
CN-1065244-C Tricyclic benzazepine vasopressin antagonists AMERICAN CYANAMID CO (US) 2001-05-02 CN disclosed
CN-1056374-C Tricyclic diazepine vasopression antagonists AMERICAN CYANAMID CO (US) 2000-09-13 CN disclosed
CN-1231666-A Tricyclic benzazepine vasopressin antagonists AMERICAN CYANAMID CO (US) 1999-10-13 CN disclosed
CN-1205335-A Tricyclic diazepine vasopression antagonists AMERICAN CYANAMID CO (US) 1999-01-20 CN disclosed
CN-1039908-C Tricyclic diaza * vasopressin antagonists and oxytocin antagonists AMERICAN CYANAMID CO (US) 1998-09-23 CN disclosed
CN-1106812-A Tricyclic diaza * vasopressin antagonists and oxytocin antagonists AMERICAN CYANAMID CO (US) 1995-08-16 CN disclosed
US-4362666-A ANTIDEPRESSANTS CIBA-GEIGY CORPORATION (US) 1982-12-07 US disclosed
US-4316900-A Piperazinopyrrolobenzodiazepines CIBA-GEIGY CORPORATION (US) 1982-02-23 US disclosed
EP-0001585-B1 PIPERAZINO-PYRROLOBENZODIAZEPINES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1981-07-22 EP disclosed
EP-0001585-A1 Piperazino-pyrrolobenzodiazepines, methods for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-05-02 EP disclosed