SCHEMBL788938

SCHEMBL788938

c1ccc2cc(-c3ccc4[nH]c5ccc(-c6cccc7c6oc6ccccc67)cc5c4c3)ccc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.53
PRKDC P78527 4/20 0.42
GGPS1 O95749 1/20 0.41
CASP3 P42574 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
SENP6 Q9GZR1 1/20 0.40
PTGES2 Q9H7Z7 1/20 0.38
HCRTR1 O43613 1/20 0.38
HTR2B P41595 1/20 0.36
HTR5A P47898 1/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
GSTP1 P09211 1/20 0.36
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
NPC1 O15118 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10226913 0.91 PRKDC (0.46) ALOX5PRKDCHTR2BHTR5AGSTP1
SCHEMBL768872 0.91 ALOX5 (0.62) ALOX5PRKDCGGPS1CASP3SENP7
SCHEMBL788998 0.90 ALOX5 (0.56) ALOX5PRKDCGGPS1CASP3SENP7
SCHEMBL18381878 0.90 ALOX5 (0.61) ALOX5PRKDCGGPS1CASP3SENP7
SCHEMBL25118713 0.89 ALOX5 (0.64) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL788870 0.88 ALOX5 (0.57) ALOX5PRKDCGGPS1CASP3SENP7
SCHEMBL788745 0.88 ALOX5 (0.57) ALOX5PRKDCGGPS1CASP3SENP7
SCHEMBL788234 0.88 PRKDC (0.45) ALOX5PRKDCHTR2BHTR5AGSTP1
SCHEMBL457912 0.88 ALOX5 (0.59) ALOX5PRKDCGGPS1CASP3SENP7
SCHEMBL30395989 0.88 ALOX5 (0.59) ALOX5PRKDCGGPS1CASP3SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885PRKDC 3567/4885GGPS1 2063/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.