SCHEMBL788998

SCHEMBL788998

c1ccc2c(-c3ccc4[nH]c5ccc(-c6cccc7c6oc6ccccc67)cc5c4c3)cccc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.56
GGPS1 O95749 1/20 0.42
PRKDC P78527 5/20 0.42
PTGES2 Q9H7Z7 1/20 0.39
KDM4E B2RXH2 2/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MCL1 Q07820 1/20 0.37
ACMSD Q8TDX5 1/20 0.37
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
CASP3 P42574 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
ALK Q9UM73 1/20 0.36
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
TLR8 Q9NR97 1/20 0.35
TLR7 Q9NYK1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL768872 0.93 ALOX5 (0.62) ALOX5GGPS1PRKDCPTGES2CASP3
SCHEMBL18381878 0.92 ALOX5 (0.61) ALOX5GGPS1PRKDCPTGES2CASP3
SCHEMBL30487044 0.91 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL457912 0.91 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL30395989 0.91 ALOX5 (0.59) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL788938 0.90 ALOX5 (0.53) ALOX5GGPS1PRKDCPTGES2CASP3
SCHEMBL18381837 0.89 ALOX5 (0.58) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL17753314 0.89 ALOX5 (0.52) ALOX5GGPS1PRKDCPTGES2
SCHEMBL788944 0.88 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2KDM4E
SCHEMBL788870 0.88 ALOX5 (0.57) ALOX5GGPS1PRKDCPTGES2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9450188-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-09-20 US disclosed
US-20140145175-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-05-29 US disclosed
US-8642782-B2 Carbazole derivative, light-emitting element material and organic semiconductor material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-02-04 US disclosed
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120071668-A1 Carbazole Derivative, Light-Emitting Element Material and Organic Semiconductor Material SLC39A3, SULT1A1, NUTF2 ALOX5 1162/4885GGPS1 2063/4885PRKDC 3567/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.