Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7890296 | 0.75 | LMNA (0.50) | LMNANPSR1CYP3A4ALDH1A1HTT | |
| SCHEMBL27474102 | 0.71 | LMNA (0.58) | LMNANPSR1ALDH1A1HTTNR4A2 | |
| SCHEMBL8041152 | 0.67 | TP53 (0.50) | LMNANPSR1ADORA2AADORA2BADORA1 | |
| SCHEMBL31061407 | 0.67 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL17502115 | 0.67 | CSNK2A2 (1.00) | CSNK2A2CSNK2BCSNK2A1ALDH1A1KDM4E | |
| SCHEMBL6512784 | 0.66 | CSNK2A2 (0.56) | CSNK2A2CSNK2BCSNK2A1LMNANPSR1 | |
| SCHEMBL7895151 | 0.66 | CSNK2A1 (0.46) | CSNK2A2CSNK2BCSNK2A1LMNAIDO1 | |
| SCHEMBL2805448 | 0.66 | CLEC4M (0.67) | CSNK2A2CSNK2BCSNK2A1TP53CYP3A4 | |
| SCHEMBL2805202 | 0.65 | CSNK2A2 (0.54) | CSNK2A2CSNK2BCSNK2A1LMNAIDO1 | |
| SCHEMBL9419140 | 0.64 | LMNA (0.44) | LMNANPSR1TP53CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180657-B1 | SLEEP DISORDERS | ELI LILLY AND COMPANY | 2001-01-30 | — | — | US | disclosed |
| WO-1997000069-A1 | MELATONIN AGONISTS FOR TREATING BENIGN PROSTATIC HYPERPLASIA | ELI LILLY AND COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |