SCHEMBL7893151

SCHEMBL7893151

Cc1cc(=O)n(-c2cccc(N)c2)[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.54
ALDH1A1 P00352 7/20 0.54
KDM4E B2RXH2 5/20 0.54
KMT2A Q03164 5/20 0.54
GAA P10253 2/20 0.54
HTT P42858 2/20 0.54
MEN1 O00255 2/20 0.54
LMNA P02545 2/20 0.51
RECQL P46063 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
TDP1 Q9NUW8 1/20 0.50
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
ALKBH5 Q6P6C2 4/20 0.47
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43
ALKBH3 Q96Q83 1/20 0.42
ALPL P05186 2/20 0.42
ENPP3 O14638 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5675303 0.83 ALKBH5 (0.65) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL4023307 0.81 MAPT (0.57) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL8166341 0.81 ALDH1A1 (0.69) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL34121 0.80 ALDH1A1 (0.68) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL5425653 0.80 ALDH1A1 (0.68) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL9150171 0.80 ALDH1A1 (0.68) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL27912588 0.80 ALKBH5 (0.61) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL27912589 0.80 ALDH1A1 (0.54) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL11780323 0.80 ALDH1A1 (0.57) MAPTALDH1A1KDM4EKMT2AGAA
SCHEMBL486408 0.79 MAPT (0.71) MAPTALDH1A1KDM4EKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5696242-A LEATHER DYES CLARIANT FINANCE (BVI) LIMITED (VG) 1997-12-09 US claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed
US-6177552-B1 CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-23 US disclosed
EP-0309406-B2 Reactive dyes, their preparation and their use CIBA SC HOLDING AG (CH) 2000-07-12 EP disclosed
EP-0838504-B1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DYSTAR TEXTILFARBEN GMBH & CO (DE) 2000-06-07 EP disclosed
US-6060591-A FOR DYEING A MATERIAL CONTAINING HYDROXY OR CARBOXAMIDE GROUPS OR BOTH DY STAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND K.G. (DE) 2000-05-09 US disclosed
US-5834601-A DYEING CELLULOSE, WOOL, POLYAMIDE DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1998-11-10 US disclosed
EP-0573809-B1 Liquid azo dye and ink composition containing the same ORIENT CHEMICAL IND (JP) 1998-08-19 EP disclosed
EP-0848042-A2 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-06-17 EP disclosed
EP-0838504-A1 Water-soluble fiber-reactive dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-04-29 EP disclosed
US-5731421-A COLORFASTNESS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-03-24 US disclosed
US-4145340-A WATER-SOLUBLE REACTIVE MONOAZO DYE CONTAINING A NONYLPHENOXY, CHLOROTRIAZINE GROUP IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-03-20 US disclosed
US-4123428-A COLORFASTNESS SANDOZ LTD. (CH) 1978-10-31 US disclosed
US-4118384-A DIAZOTIZATION BAYER AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed
US-4089895-A COUPLER FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1978-05-16 US disclosed
US-4035350-A Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-12 US disclosed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US disclosed
US-3981677-A Oxidative hair dye compositions containing N-substituted o-phenylenediamines and method for their use CLAIROL INCORPORATED (US) 1976-09-21 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US disclosed