Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrene SCHEMBL717394 | 0.83 | ALDH1A1 (0.73) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Pyrene SCHEMBL789425 | 0.83 | ALDH1A1 (0.73) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Pyrene SCHEMBL1332849 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Pyrene SCHEMBL29429699 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Pyrene SCHEMBL1650929 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Pyrene SCHEMBL9130 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Pyrene SCHEMBL223412 | 0.76 | ALDH1A1 (1.00) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Anthracene SCHEMBL25336969 | 0.76 | CYP1A2 (0.40) | ALDH1A1HSD17B10HPGDCYP1A2CYP3A4 | |
| Pyrene SCHEMBL1829255 | 0.74 | ALDH1A1 (0.79) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 | |
| Pyrene SCHEMBL28304707 | 0.74 | ALDH1A1 (0.79) | ALDH1A1HSD17B10HPGDTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11213800-B2 | Covalent organic framework films, and methods of making and uses of same | CORNELL UNIVERSITY (US) | 2022-01-04 | — | — | US | disclosed |
| US-20140148596-A1 | Covalent Organic Frameworks and Methods of Making Same | CORNELL UNIVERSITY (US) | 2014-05-29 | — | — | US | disclosed |
| US-20140037944-A1 | COVALENT ORGANIC FRAMEWORK FILMS, AND METHODS OF MAKING AND USES OF SAME | CORNELL UNIVERSITY (US) | 2014-02-06 | — | — | US | disclosed |
| WO-2012037090-A2 | COVALENT ORGANIC FRAMEWORK FILMS, AND METHODS OF MAKING AND USES OF SAME | CORNELL UNIVERSITY (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2011127301-A2 | COVALENT ORGANIC FRAMEWORKS AND METHODS OF MAKING SAME | CORNELL UNIVERSITY (US) | 2011-10-13 | — | — | WO | disclosed |