Pyrene

Pyrene

SCHEMBL717394

OBO.c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.73
▸ HSD17B10 Q99714 6/20 0.73
▸ HPGD P15428 6/20 0.73
▸ TSHR P16473 5/20 0.73
▸ CYP3A4 P08684 3/20 0.73
▸ CYP1A2 P05177 3/20 0.73
▸ CYP1A1 P04798 2/20 0.73
▸ CYP1B1 Q16678 2/20 0.73
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ THRB P10828 1/20 0.48
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ TDP1 Q9NUW8 2/20 0.46
▸ MAPK1 P28482 2/20 0.43
▸ ATM Q13315 1/20 0.43
▸ ERBB2 P04626 1/20 0.42
▸ FYN P06241 1/20 0.42
▸ MAOA P21397 1/20 0.42
▸ ACHE P22303 1/20 0.42
▸ AHR P35869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL789425 1.00 ALDH1A1 (0.73) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL29429699 0.86 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL1650929 0.86 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL9130 0.86 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL223412 0.86 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL1332849 0.86 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL789426 0.83 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL1829255 0.83 ALDH1A1 (0.79) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL28304707 0.83 ALDH1A1 (0.79) ALDH1A1HSD17B10HPGDTSHRCYP3A4
Pyrene SCHEMBL23319293 0.82 ALDH1A1 (0.92) ALDH1A1HSD17B10HPGDTSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250258130-A1 POLAR FLUID GATED FIELD EFFECT DEVICES GRAPHWEAR TECHNOLOGIES INC. 2025-08-14 — — US claimed
US-12298215-B2 Polar fluid gated field effect devices GRAPHWEAR TECHNOLOGIES INC. (US) 2025-05-13 — — US claimed
CN-118878402-A Preparation method of trifluoromethyl ketone compound based on palladium catalysis of C-N bond cleavage 大连理工大学 2024-11-01 — — CN claimed
CN-117865773-A Preparation method of difluoromethyl aromatic compound based on palladium-catalyzed decarbonylation coupling 大连理工大学 2024-04-12 — — CN claimed
CN-109642888-B Polar fluid gated field effect device 格拉夫威尔科技公司 2022-11-01 — — CN claimed
EP-3768159-A1 REPLACEABLE SENSOR SYSTEMS AND METHODS Graphwear Technologies Inc. (US) 2021-01-27 — — EP claimed
WO-2019183279-A1 REPLACEABLE SENSOR SYSTEMS AND METHODS GRAPHWEAR TECHNOLOGIES INC. (US) 2019-09-26 — — WO claimed
US-20190257732-A1 POLAR FLUID GATED FIELD EFFECT DEVICES GRAPHWEAR TECHNOLOGIES INC. 2019-08-22 — — US claimed
EP-3472607-A2 POLAR FLUID GATED FIELD EFFECT DEVICES Graphwear Technologies Inc. (US) 2019-04-24 — — EP claimed
WO-2017216641-A2 POLAR FLUID GATED FIELD EFFECT DEVICES GRAPHWEAR TECHNOLOGIES INC. (US) 2017-12-21 — — WO claimed
US-8969069-B2 Glycated protein measurement sensor and portable glycated protein measurement apparatus including same NDD, INC. (KR) 2015-03-03 — — US claimed
US-20140335629-A1 GLYCATED PROTEIN MEASUREMENT SENSOR AND PORTABLE GLYCATED PROTEIN MEASUREMENT APPARATUS INCLUDING SAME IM HEALTHCARE CO., LTD. (KR) 2014-11-13 — — US claimed
EP-2762871-A2 GLYCATED PROTEIN MEASUREMENT SENSOR AND PORTABLE GLYCATED PROTEIN MEASUREMENT APPARATUS INCLUDING SAME Ndd, Inc. (KR) 2014-08-06 — — EP claimed
US-20250258130-A1 POLAR FLUID GATED FIELD EFFECT DEVICES GRAPHWEAR TECHNOLOGIES INC. 2025-08-14 — — US disclosed
US-12325031-B2 Graphene-based dielectrophoresis sensor and method REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2025-06-10 — — US disclosed
US-12298215-B2 Polar fluid gated field effect devices GRAPHWEAR TECHNOLOGIES INC. (US) 2025-05-13 — — US disclosed
US-20090004108-A1 Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors MASIMO LABORATORIES, INC. (US) 2009-01-01 — — US disclosed
WO-2008153930-A1 SENSORS FOR THE DETECTION OF DIOLS AND CARBOHYDRATES USING BORONIC ACID CHELATORS FOR GLUCOSE THE CHARLES STARK DRAPER LABORATORY, INC. (US) 2008-12-18 — — WO disclosed
US-20070110672-A1 SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors CERCACOR LABORATORIES, INC. 2007-05-17 — — US disclosed
WO-2005065241-A2 SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS ARGOSE, INC. (US) 2005-07-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070110672-A1 SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors GCKR, SYMPK, SUCNR1 ALDH1A1 4364/4885HSD17B10 1033/4885HPGD 1172/4885
US-20090004108-A1 Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors GCKR, SYMPK, SUCNR1 ALDH1A1 4364/4885HSD17B10 1033/4885HPGD 1172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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