Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886819 | 0.93 | VCP (0.58) | VCP | |
| SCHEMBL7886664 | 0.82 | VCP (0.54) | VCP | |
| SCHEMBL7896436 | 0.82 | VCP (0.51) | VCP | |
| SCHEMBL7893630 | 0.76 | MEN1 (0.44) | VCP | |
| Acetic Acid SCHEMBL29049224 | 0.64 | HSD17B10 (0.56) | — | |
| Acetic Acid SCHEMBL27637376 | 0.64 | GAA (0.66) | — | |
| SCHEMBL25377223 | 0.63 | PKM (0.53) | — | |
| Bicarbonate SCHEMBL29049243 | 0.63 | HSD17B10 (0.58) | — | |
| SCHEMBL3789793 | 0.63 | P2RX7 (0.47) | — | |
| SCHEMBL11217670 | 0.63 | CXCR4 (0.56) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085246-A1 | 2,4-DIAMINO-1,3,5-TRIAZINE AND 4, 6-DIAMINO-PYRIMIDINE DERIVATIVES AND THEIR USE AS AGGRECANASE INHIBITORS | PRAECIS PHARMACEUTICALS INC (US) | 2010-07-29 | — | — | WO | disclosed |