Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7894407 | 0.82 | HDAC4 (0.38) | L3MBTL1ALDH1A1HDAC4KMT2ACYP2C19 | |
| SCHEMBL17374488 | 0.71 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL17883760 | 0.71 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL18426527 | 0.71 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL28179357 | 0.68 | CYP1A2 (0.43) | L3MBTL1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL16976697 | 0.67 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL12605298 | 0.67 | ALDH1A1 (0.43) | L3MBTL1ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL12861394 | 0.67 | CHRNB2 (0.46) | L3MBTL1ALDH1A1ATMSMN1; SMN2NPSR1 | |
| SCHEMBL3779237 | 0.66 | ALDH1A1 (0.42) | ALDH1A1NPSR1MAPTRAB9AKMT2A | |
| SCHEMBL11393341 | 0.66 | ALDH1A1 (0.39) | L3MBTL1ALDH1A1MAPTITGA4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180611-B1 | INHIBITORS OF MATRIX METALLOPROTEINASES AND TUMOR NECROSIS FACTOR | DARWIN DISCOVERY, LTD. (GB) | 2001-01-30 | — | — | US | disclosed |
| US-5994312-A | Peptidyl compounds | DARWIN DISCOVERY, LTD. (GB) | 1999-11-30 | — | — | US | disclosed |