Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3705174 | 0.87 | PPARG (0.42) | XDHNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7895901 | 0.86 | CDC7 (0.52) | XDHNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL3703462 | 0.84 | XDH (0.55) | XDH | |
| SCHEMBL3716982 | 0.83 | THRA (0.43) | XDHNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7896260 | 0.79 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL7890950 | 0.78 | XDH (0.45) | XDHNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7894648 | 0.77 | ICMT (0.45) | XDH | |
| SCHEMBL3703443 | 0.74 | XDH (0.59) | XDH | |
| SCHEMBL7892923 | 0.74 | KDM4C (0.42) | — | |
| SCHEMBL3707163 | 0.73 | CDC7 (0.52) | XDHNPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010093191-A2 | NOVEL COMPOUNDS EFFECTIVE AS XANTHINE OXIDASE INHIBITORS, METHOD FOR PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2010-08-19 | — | — | WO | disclosed |