Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 5/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 5/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789969 | 0.81 | RAB9A (0.45) | ALDH1A1MITFRAB9AKDM4ELMNA | |
| SCHEMBL10087865 | 0.77 | TRPC3 (0.58) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL790044 | 0.65 | TRPC3 (0.71) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL789018 | 0.64 | TRPC3 (0.66) | TRPC3TRPC6TRPA1CACNA1CSCN5A | |
| SCHEMBL156202 | 0.63 | HRH3 (0.76) | ALDH1A1MITFRAB9AKDM4EACHE | |
| SCHEMBL12158158 | 0.62 | DHODH (0.69) | ALDH1A1RAB9AKDM4ELMNAHPGD | |
| SCHEMBL12158167 | 0.62 | MAPT (0.54) | ALDH1A1RAB9AKDM4ELMNAHPGD | |
| SCHEMBL12158116 | 0.62 | MAPT (0.42) | CYP1A2CYP2C9CYP2C19ALDH1A1RAB9A | |
| SCHEMBL12158209 | 0.61 | DHODH (0.62) | ALDH1A1RAB9AKDM4ELMNAHPGD | |
| SCHEMBL4513933 | 0.61 | HRH3 (0.67) | ALDH1A1KDM4EACHEHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037351-A1 | COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |