Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.31 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24032646 | 0.86 | POLB (0.38) | POLBHTR1DGABRA1GABRB2HTR1B | |
| SCHEMBL246694 | 0.81 | POLB (0.40) | POLBHTR1DGABRA1GABRB2CYP1A2 | |
| SCHEMBL7941412 | 0.81 | POLB (0.40) | POLBHTR1DGABRA1GABRB2CYP1A2 | |
| SCHEMBL1859057 | 0.77 | POLB (0.34) | POLBHTR1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL39338 | 0.76 | POLB (0.36) | POLBHTR1DGABRA1GABRB2CYP1A2 | |
| SCHEMBL1859062 | 0.75 | CYP1A2 (0.33) | POLBHTR1DGABRA1GABRB2CYP1A2 | |
| SCHEMBL76615 | 0.75 | POLB (0.35) | POLBHTR1DCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL460101 | 0.75 | ALDH1A1 (0.36) | POLBHTR1DCYP1A2TSHRCYP2C9 | |
| SCHEMBL7943072 | 0.73 | GABRA1 (0.42) | POLBHTR1DGABRA1GABRB2CYP1A2 | |
| SCHEMBL789567 | 0.73 | HMGCR (0.36) | POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3135929-A | — | — | None | — | — | JP | disclosed |
| JP-H03135929-A | SIMULTANEOUS PRODUCTION OF 2,5-DICHLOROTOLUENE AND 2,6-DICHLOROTOLUENE | KUREHA CHEM IND CO LTD | 1991-06-10 | — | — | JP | disclosed |