Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC25A5 | P05141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896034 | 0.66 | KDM4E (0.35) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL13649105 | 0.62 | SLC25A5 (0.35) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL29957759 | 0.61 | KDM4E (0.32) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL29351523 | 0.60 | ALOX5 (0.61) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL29934449 | 0.58 | ALOX5 (0.54) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL13629033 | 0.56 | KDM4E (0.72) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL31576826 | 0.56 | ALOX5 (0.55) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL12729608 | 0.56 | SLC25A5 (0.37) | SLC25A5 | |
| SCHEMBL2439244 | 0.56 | ALOX5 (0.37) | ALOX5KDM4EMEN1AKR1B10KMT2A | |
| SCHEMBL31576804 | 0.55 | ALOX5 (0.51) | ALOX5KDM4EMEN1AKR1B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177474-B1 | AROMATIC COMPOUND CONTAINING KETONE AND HYDROXY GROUPS | HOECHST MARION ROUSSEL (FR) | 2001-01-23 | — | — | US | disclosed |
| EP-0994093-A1 | POLYHYDROXYPHENOL DERIVATIVES AND PREVENTIVE AND THERAPEUTIC AGENTS FOR BONE AND CARTILAGE DISEASES CONTAINING THE SAME | Hoechst Marion Roussel, Ltd. (JP) | 2000-04-19 | — | — | EP | disclosed |