Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887568 | 0.95 | MAPT (0.42) | NR2E1LMNACNR1CNR2GPR55 | |
| SCHEMBL276044 | 0.90 | NPC1 (0.43) | ADRB2ADRB1LMNAGAAMAPK10 | |
| SCHEMBL14202624 | 0.88 | ADRB2 (0.42) | ADRB2ADRB1LMNAGAAMAPK10 | |
| SCHEMBL8388708 | 0.88 | ALOX15 (0.43) | ADRB2ADRB1LMNAGAAMAPK10 | |
| SCHEMBL12755352 | 0.87 | LMNA (0.45) | ADRB2ADRB1LMNAGAAMAPK10 | |
| SCHEMBL14274500 | 0.87 | CHRNA7 (0.44) | LMNAGAAMEN1KMT2ATSHR | |
| SCHEMBL15005560 | 0.87 | LMNA (0.50) | ADRB2ADRB1LMNAGAAMAPK10 | |
| SCHEMBL14793445 | 0.85 | FGFR1 (0.46) | LMNAGAAMAPK10CNR1CNR2 | |
| SCHEMBL769388 | 0.85 | MAPT (0.38) | ADRB2ADRB1LMNAGAAMAPK10 | |
| SCHEMBL29353912 | 0.85 | MAPT (0.38) | ADRB2ADRB1LMNAGAAMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6221342-B1 | PROTECTING HUMAN AND ANIMAL SKIN AND HAIR FROM THE DAMAGING EFFECT OF UV RADIATION | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-04-24 | — | — | US | disclosed |
| EP-1005325-A1 | COSMETIC USE OF BIS(RESORCINYL)TRIAZINE DERIVATIVES | Ciba SC Holding AG (CH) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999008653-A1 | COSMETIC USE OF BIS(RESORCINYL)TRIAZINE DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1999-02-25 | — | — | WO | disclosed |