Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8216433 | 0.92 | LMNA (0.42) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL14274500 | 0.91 | CHRNA7 (0.44) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL14202624 | 0.90 | ADRB2 (0.42) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL14793445 | 0.90 | FGFR1 (0.46) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL8383224 | 0.90 | PLA2G4B (0.42) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL8517433 | 0.90 | PLA2G4B (0.42) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL12755352 | 0.89 | LMNA (0.45) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL7896079 | 0.88 | NR2E1 (0.43) | ALOX15ADORA3TSHRADORA2AADORA2B | |
| SCHEMBL6334661 | 0.88 | PLA2G4B (0.41) | MAPTLMNAGAAMAPK10CNR1 | |
| SCHEMBL7887570 | 0.87 | MAPT (0.43) | MAPTNPSR1LMNAGAAMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912531-A1 | POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS | Ciba SC Holding AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003489-A1 | POLYOXYALKENE SUBSTITUTED AND BRIDGED TRIAZINE, BENZOTRIAZOLE AND BENZOPHENONE DERIVATIVES AS UV ABSORBERS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-01-29 | — | — | WO | disclosed |