Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896175 | 0.81 | — | — | |
| SCHEMBL9530846 | 0.79 | — | — | |
| SCHEMBL7903484 | 0.63 | SIGMAR1 (0.34) | — | |
| SCHEMBL7904391 | 0.60 | OPRD1 (0.32) | — | |
| SCHEMBL7903538 | 0.59 | HTR1A (0.37) | — | |
| SCHEMBL11042701 | 0.57 | CYP2D6 (0.40) | ALOX5 | |
| SCHEMBL7908075 | 0.56 | HTR1A (0.48) | — | |
| SCHEMBL9526261 | 0.56 | HTR1A (0.54) | — | |
| SCHEMBL7395375 | 0.53 | HTR2C (0.48) | ALOX5 | |
| SCHEMBL14260177 | 0.51 | SIGMAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6201119-B1 | 2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPIN-9-AMINE COMPOUNDS USEFUL AS INTERMEDIATES TO ANTIVIRALS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-03-13 | — | — | US | disclosed |
| US-5371079-A | Administering to inhibit replication of HIV-1 in human cells | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-12-06 | — | — | US | disclosed |
| US-5270464-A | Anti-HIV-1 tetrahydroimidazo[1,4]benzodiazepin-2-(thi) ones | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-12-14 | — | — | US | disclosed |