Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27522728 | 0.89 | ALOX5 (0.48) | TSHRALDH1A1ALOX5CYP1A2CNR1 | |
| SCHEMBL1022491 | 0.84 | ALDH1A1 (0.54) | TSHRALDH1A1CYP1A2HSP90AA1HSD17B10 | |
| SCHEMBL4456487 | 0.84 | CYP1A2 (0.50) | TSHRALDH1A1CYP1A2CNR1HSD17B10 | |
| SCHEMBL2939513 | 0.79 | ALOX15 (0.43) | TSHRALDH1A1ALOX5CYP1A2AR | |
| SCHEMBL4997683 | 0.79 | TSHR (0.59) | TSHRALDH1A1ALOX5CYP1A2HSP90AA1 | |
| SCHEMBL25893532 | 0.78 | ALOX5 (0.44) | TSHRALDH1A1ALOX5CYP1A2CNR1 | |
| SCHEMBL28066782 | 0.75 | ESR1 (0.48) | TSHRALDH1A1HSD17B10HSD17B1HSD17B2 | |
| SCHEMBL2934393 | 0.74 | ALDH1A1 (0.46) | TSHRALDH1A1ALOX5CYP1A2AR | |
| SCHEMBL14860351 | 0.74 | GRIA1 (0.51) | TSHRALDH1A1CYP1A2TNKSTNKS2 | |
| SCHEMBL25501416 | 0.74 | CYP1A2 (0.41) | TSHRALDH1A1CYP1A2CNR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6190759-B1 | ELECTRONIC PACKAGE COMPRISING DIELECTRIC LAYER AND CONDUCTIVE LAYER, SAID DIELECTRIC LAYER INCLUDING REINFORCING MATERIAL, RESIN MATERIAL SELECTED FROM EPOXY, CYANATE AND BISMALEIMIDE RESINS, COLORING AGENT, AND FLUORESCING AGENT | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-02-20 | — | — | US | disclosed |
| US-6187417-B1 | Substrate having high optical contrast and method of making same | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-02-13 | — | — | US | disclosed |
| US-5238773-A | Alkaline developable photoresist composition containing radiation sensitive organosilicon compound with quinone diazide terminal groups | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0365881-A2 | Composition capable of being imaged and use of such a composition | International Business Machines Corporation (US) | 1990-05-02 | — | — | EP | disclosed |