Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CCR4 | P51679 | 1/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL790162 | 0.85 | ALDH1A1 (0.51) | PIK3CAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL3125256 | 0.80 | PIK3CG (0.61) | PIK3CAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL789433 | 0.79 | PIK3CG (0.48) | PIK3CAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL790432 | 0.77 | PIK3CA (0.45) | PIK3CAALDH1A1CCR4SLC40A1PIK3CG | |
| SCHEMBL807072 | 0.77 | GAA (0.49) | PIK3CAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL731743 | 0.77 | PIK3CD (0.70) | PIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL22230597 | 0.77 | SLC40A1 (0.49) | PIK3CAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL13199678 | 0.76 | MEN1 (0.55) | PIK3CAALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL16722048 | 0.76 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL16722050 | 0.76 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |