Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791191 | 0.88 | PDGFRB (0.44) | PIK3CAPDGFRBKDRALPLBRD4 | |
| SCHEMBL9955288 | 0.83 | PIK3CG (0.52) | PIK3CAPDGFRBKDRALPLBRD4 | |
| SCHEMBL29555684 | 0.82 | PIK3CD (0.57) | PIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL3115744 | 0.82 | PIK3CD (0.57) | PIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL791429 | 0.82 | ALPL (0.47) | PIK3CAPDGFRBKDRALPLBRD4 | |
| SCHEMBL790824 | 0.81 | ALPL (0.56) | PIK3CAPDGFRBKDRALPLSLC40A1 | |
| SCHEMBL29556839 | 0.81 | ALPL (0.56) | PIK3CAPDGFRBKDRALPLSLC40A1 | |
| SCHEMBL789981 | 0.79 | ALPL (0.48) | PIK3CAPDGFRBKDRALPLSLC40A1 | |
| SCHEMBL789780 | 0.77 | PIK3CA (0.51) | PIK3CABRD4SLC40A1PIK3CGPIK3CD | |
| SCHEMBL14247499 | 0.76 | POLB (0.55) | PDGFRBKDRALPLPIK3CGHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |