Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.56 |
| ▸ | MMP13 | P45452 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP3 | P08254 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7510496 | 0.90 | MMP2 (0.58) | MMP2MMP13MMP1MMP3CA12 | |
| SCHEMBL7502706 | 0.83 | MMP13 (0.50) | MMP2MMP13MMP1MMP3CA12 | |
| SCHEMBL7502278 | 0.83 | MMP13 (0.55) | MMP2MMP13MMP1MMP3CA12 | |
| SCHEMBL7572580 | 0.79 | MMP13 (0.39) | MMP2MMP13MMP1MMP3CA12 | |
| SCHEMBL7502964 | 0.78 | MMP13 (0.50) | MMP2MMP13MMP1MMP3CA12 | |
| SCHEMBL7587417 | 0.77 | ALDH1A1 (0.41) | CA12CA2CA9MEN1KMT2A | |
| SCHEMBL7451387 | 0.74 | MMP13 (0.83) | MMP2MMP13MMP1MMP3MMP9 | |
| SCHEMBL7516820 | 0.74 | MMP13 (0.54) | MMP2MMP13MMP1MMP3CA12 | |
| SCHEMBL7456196 | 0.73 | MMP2 (0.35) | MMP2MMP13MMP1MMP3CA12 | |
| SCHEMBL7450645 | 0.72 | MMP13 (0.44) | MMP2MMP13MMP1MMP3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |