Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 14/20 | 0.39 |
| ▸ | MMP2 | P08253 | 11/20 | 0.39 |
| ▸ | MMP3 | P08254 | 11/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502964 | 0.88 | MMP13 (0.50) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7502278 | 0.86 | MMP13 (0.55) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7587417 | 0.86 | ALDH1A1 (0.41) | CA12CA1CA2CA9HTT | |
| SCHEMBL7502706 | 0.86 | MMP13 (0.50) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7451550 | 0.82 | MMP2 (0.46) | MMP13MMP2MMP3MMP1CA12 | |
| SCHEMBL7450581 | 0.81 | MMP2 (0.49) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7898486 | 0.79 | MMP2 (0.56) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7512865 | 0.78 | KMT2A (0.39) | MMP13MMP2MMP3MMP1MMP9 | |
| SCHEMBL7547380 | 0.77 | MMP2 (0.41) | MMP13MMP2MMP3MMP1HTT | |
| SCHEMBL7516820 | 0.76 | MMP13 (0.54) | MMP13MMP2MMP3MMP1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165501-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-01-02 | — | — | EP | disclosed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |
| WO-2000051975-A1 | ALKENYL- AND ALKYNYL-CONTAINING METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-08 | — | — | WO | disclosed |