Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7891157 | 0.89 | KDM4E (0.35) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7903335 | 0.82 | MAPT (0.38) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7898341 | 0.81 | KDM4E (0.40) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7896605 | 0.77 | MAPT (0.39) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7899991 | 0.77 | CHRNB2 (0.35) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7898288 | 0.73 | KIF11 (0.39) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7892484 | 0.70 | CYP2A6 (0.39) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7899671 | 0.69 | KDM4E (0.44) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7898968 | 0.68 | CHRNB2 (0.46) | KDM4EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7899655 | 0.64 | CHRNB2 (0.42) | KDM4EMAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |