Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898288 | 0.80 | KIF11 (0.39) | KDM4EMAPK1MEN1MAPTKMT2A | |
| SCHEMBL7891188 | 0.78 | PARP1 (0.42) | KDM4EMAPK1MEN1MAPTKMT2A | |
| SCHEMBL7903335 | 0.77 | MAPT (0.38) | KDM4EMAPK1MEN1MAPTKMT2A | |
| SCHEMBL7898341 | 0.73 | KDM4E (0.40) | KDM4EMAPK1MEN1MAPTKMT2A | |
| SCHEMBL7899991 | 0.72 | CHRNB2 (0.35) | KDM4EMAPK1MEN1MAPTKMT2A | |
| SCHEMBL7896605 | 0.72 | MAPT (0.39) | KDM4EMAPK1MEN1MAPTKMT2A | |
| SCHEMBL17916263 | 0.71 | NLRP3 (0.45) | KDM4EMAPK1MEN1MAPTKMT2A | |
| SCHEMBL18269674 | 0.69 | HTR5A (0.41) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL18324164 | 0.69 | HTR5A (0.41) | KDM4EMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL7571638 | 0.69 | HTR5A (0.41) | KDM4EMEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |