Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 11/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.52 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | CD40 | P25942 | 1/20 | 0.46 |
| ▸ | CD40LG | P29965 | 1/20 | 0.46 |
| ▸ | MPL | P40238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899064 | 1.00 | PHLPP2 (0.58) | PHLPP2ENPP2PRMT1CARM1PRMT3 | |
| SCHEMBL29702399 | 0.89 | ENPP2 (0.58) | PHLPP2ENPP2PRMT1PRMT3EP300 | |
| SCHEMBL29702431 | 0.88 | ENPP2 (0.59) | PHLPP2ENPP2PRMT1PRMT3EP300 | |
| SCHEMBL7770984 | 0.88 | PHLPP2 (0.62) | PHLPP2ENPP2PRMT1CARM1CD40 | |
| SCHEMBL8059751 | 0.88 | PHLPP2 (0.62) | PHLPP2ENPP2PRMT1CARM1CD40 | |
| SCHEMBL13631321 | 0.87 | ENPP2 (0.54) | PHLPP2ENPP2PRMT1PRMT3EP300 | |
| SCHEMBL20306679 | 0.87 | ENPP2 (0.54) | PHLPP2ENPP2PRMT1PRMT3EP300 | |
| SCHEMBL7899050 | 0.86 | PRMT1 (0.48) | PHLPP2ENPP2PRMT1CARM1PRMT3 | |
| SCHEMBL8414600 | 0.86 | PRMT3 (0.61) | PHLPP2ENPP2PRMT1PRMT3EP300 | |
| SCHEMBL13474894 | 0.86 | ENPP2 (0.60) | PHLPP2ENPP2PRMT1PRMT3EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058276-A1 | 7-AMINO-4-HYDROXY-3-(4-METHOXY-PHENYLAZO)-NAPHTHALENE-2-SULFONIC ACID DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |
| US-6200963-B1 | USEFUL AS FEMALE AND MALE CONTRACEPTIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-03-13 | — | — | US | disclosed |
| WO-2000058276-A1 | 7-AMINO-4-HYDROXY-3-(4-METHOXY-PHENYLAZO)-NAPHTHALENE-2-SULFONIC ACID DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000058276-A1 | 7-AMINO-4-HYDROXY-3-(4-METHOXY-PHENYLAZO)-NAPHTHALENE-2-SULFONIC ACID DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |