Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | EIF4E | P06730 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30592857 | 0.84 | TDP1 (0.57) | DHODHTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL18201 | 0.84 | TDP1 (0.57) | DHODHTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL975732 | 0.84 | HDAC6 (0.53) | DHODHTDP1EIF4EKDM4EALDH1A1 | |
| SCHEMBL25263246 | 0.83 | DHODH (0.50) | DHODHEIF4EBTK | |
| SCHEMBL2772323 | 0.78 | DHODH (0.46) | DHODHEIF4EKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL8686364 | 0.77 | P2RX7 (0.49) | DHODHTDP1MAPK1KDM4EALDH1A1 | |
| SCHEMBL2042515 | 0.76 | DHODH (0.58) | DHODHEIF4ERAB9ANPC1BTK | |
| SCHEMBL29788287 | 0.76 | DHODH (0.58) | DHODHEIF4ERAB9ANPC1BTK | |
| SCHEMBL11378953 | 0.76 | ALDH1A1 (0.69) | DHODHTDP1KDM4EALDH1A1NPSR1 | |
| SCHEMBL10668402 | 0.76 | BTK (0.49) | DHODHTDP1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323227-B1 | PRODRUGS | AVENTIS PHARMACEUTICALS PRODUCTS INC. | 2001-11-27 | — | — | US | disclosed |