SCHEMBL18201

SCHEMBL18201

COc1ncccc1C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.57
KDM4E B2RXH2 2/20 0.57
ALDH1A1 P00352 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
MAPT P10636 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
CYP3A4 P08684 1/20 0.55
ALOX15 P16050 1/20 0.55
TSHR P16473 1/20 0.55
BLM P54132 1/20 0.55
AGER Q15109 1/20 0.55
NAPRT Q6XQN6 2/20 0.53
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
POLB P06746 1/20 0.53
HTT P42858 3/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
GAA P10253 1/20 0.50
DHODH Q02127 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30592857 1.00 TDP1 (0.57) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL8686364 0.92 P2RX7 (0.49) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL31182075 0.87 TDP1 (0.52) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL949562 0.86 TDP1 (0.50) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL31081770 0.85 TDP1 (0.49) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL8427582 0.85 TDP1 (0.49) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL7899073 0.84 DHODH (0.56) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL6457226 0.83 TDP1 (0.64) TDP1ALDH1A1NPSR1MAPTHTT
SCHEMBL5073283 0.83 TDP1 (0.47) TDP1KDM4EALDH1A1NPSR1MAPT
SCHEMBL6609846 0.83 TDP1 (0.47) TDP1KDM4EALDH1A1NPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313835-A1 MICELLAR NANOPARTICLES AND USES THEREOF BIORCHESTRA CO., LTD. (KR) 2025-10-09 US claimed
WO-2025149946-A1 MICELLAR NANOPARTICLES AND USES THEREOF BIORCHESTRA CO., LTD. (KR) 2025-07-17 WO claimed
EP-4551193-A1 MICELLAR NANOPARTICLES AND USES THEREOF Biorchestra Co., Ltd. (KR) 2025-05-14 EP claimed
CN-119431432-A Andrographolide diester derivative, preparation method and application 西北农林科技大学 2025-02-14 CN claimed
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
WO-2024009268-A1 MICELLAR NANOPARTICLES AND USES THEREOF BIORCHESTRA CO., LTD. (KR) 2024-01-11 WO claimed
CN-113912592-B Honokiol dihydrofuran ester derivative, preparation method and application thereof 西北农林科技大学 2023-03-10 CN claimed
CN-114436952-A Synthesis method of 2-methoxy-3-amino-5-pyridine boronic acid pinacol ester and intermediate thereof 杭州珠联医药科技有限公司 2022-05-06 CN claimed
CN-113912592-A Honokiol dihydrofuran ester derivative, preparation method and application thereof 西北农林科技大学 2022-01-11 CN claimed
EP-3568474-A1 MODULATING EXPRESSION OF POLYPEPTIDES VIA NEW GENE SWITCH EXPRESSION SYSTEMS Intrexon Corporation (US) 2019-11-20 EP claimed
WO-2018132494-A1 MODULATING EXPRESSION OF POLYPEPTIDES VIA NEW GENE SWITCH EXPRESSION SYSTEMS INTREXON CORPORATION (US) 2018-07-19 WO claimed
WO-2008013334-A1 DEFORMYLASE INHIBITOR, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2008-01-31 WO claimed
EP-1601642-A4 BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX RHEOGENE INC (US) 2007-04-11 EP claimed
EP-1601642-A2 BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX RheoGene, Inc. (US) 2005-12-07 EP claimed
WO-2004078924-A2 BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX RHEOGENE, INC. (US) 2004-09-16 WO claimed
EP-0289180-B1 METHOD OF CHLORINATION PFIZER INC. (US) 1992-12-02 EP claimed
EP-0289180-A2 Method of chlorination PFIZER INC. (US) 1988-11-02 EP claimed
US-4716231-A Chlorination of 2-methoxynicotinic acid PFIZER INC. (US) 1987-12-29 US claimed
US-20260138991-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES MOMA THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-3879403-A BENZENESULFONYLUREA DERIVATIVES PFIZER 1975-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260138991-A1 SEMI-SATURATED BICYCLIC DERIVATIVES AND RELATED USES POLA1, SUB1, CTDSP1 TDP1 21/4885KDM4E 4515/4885ALDH1A1 840/4885
US-20250313835-A1 MICELLAR NANOPARTICLES AND USES THEREOF HNRNPLL, UACA, POLRMT TDP1 395/4885KDM4E 4318/4885ALDH1A1 4319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.