SCHEMBL7899078

SCHEMBL7899078

COc1ccc(C(SC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DUT P33316 4/20 0.59
TYMS P04818 3/20 0.45
KIF11 P52732 5/20 0.40
P2RY14 Q15391 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7908347 0.86 TK1 (0.51) TYMS
SCHEMBL912656 0.85 DUT (0.60) DUTTYMSP2RY14
SCHEMBL912657 0.85 DUT (0.60) DUTTYMSP2RY14
SCHEMBL13463839 0.85 DUT (0.60) DUTTYMSP2RY14
SCHEMBL13444851 0.85 DUT (0.60) DUTTYMSP2RY14
SCHEMBL19841219 0.85 DUT (0.60) DUTTYMSP2RY14
SCHEMBL14403996 0.85 DUT (0.60) DUTTYMSP2RY14
SCHEMBL13463976 0.84 DUT (0.84) DUTTYMS
SCHEMBL13444852 0.84 DUT (0.84) DUTTYMS
SCHEMBL9345125 0.84 DUT (0.84) DUTTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197949-B1 SUPPORTS AND NOVEL PROCESSES FOR BINDING OLIGONUCLEOTIDES CIS BIO INTERNATIONAL (FR) 2001-03-06 US disclosed
US-5837859-A COPOLYMER AND NUCLEOTIDES OR HYBRIDS CIS BIO INTERNATIONAL (FR) 1998-11-17 US disclosed
EP-0691978-B1 ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF CIS BIO INT (FR) 1997-10-08 EP disclosed
EP-0691978-A1 ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF CIS BIO INT (FR) 1996-01-17 EP disclosed
WO-1994022889-A1 ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF CIS BIO INTERNATIONAL (FR) 1994-10-13 WO disclosed