SCHEMBL7908347

SCHEMBL7908347

COc1ccc(C(SC[C@H]2O[C@@H](n3cc(C)c(=O)[nH]c3=O)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 3/20 0.51
TYMS P04818 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1883691 0.93 TK1 (0.55) TK1
SCHEMBL1883689 0.93 TK1 (0.55) TK1
SCHEMBL8438746 0.87 TK1 (0.54) TK1TYMS
SCHEMBL8438743 0.87 TK1 (0.54) TK1TYMS
SCHEMBL6514654 0.86 RNASE1 (0.48) TK1
SCHEMBL7899078 0.86 DUT (0.59) TYMS
SCHEMBL23517951 0.85 TYMS (0.56) TK1TYMS
SCHEMBL22984023 0.85 TYMS (0.56) TK1TYMS
SCHEMBL22983972 0.85 TYMS (0.56) TK1TYMS
SCHEMBL7535874 0.85 TYMS (0.56) TK1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6197949-B1 SUPPORTS AND NOVEL PROCESSES FOR BINDING OLIGONUCLEOTIDES CIS BIO INTERNATIONAL (FR) 2001-03-06 US disclosed
US-5837859-A COPOLYMER AND NUCLEOTIDES OR HYBRIDS CIS BIO INTERNATIONAL (FR) 1998-11-17 US disclosed
EP-0691978-B1 ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF CIS BIO INT (FR) 1997-10-08 EP disclosed
EP-0691978-A1 ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF CIS BIO INT (FR) 1996-01-17 EP disclosed
WO-1994022889-A1 ELECTRONICALLY CONDUCTIVE POLYMER/NUCLEOTIDE COPOLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF CIS BIO INTERNATIONAL (FR) 1994-10-13 WO disclosed