SCHEMBL7899181

SCHEMBL7899181

C#CC(C)Oc1cc(-n2c(=O)cc(C(F)(F)F)n3ccnc23)c(F)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
BCAT2 O15382 2/20 0.32
BCAT1 P54687 2/20 0.32
PPOX P50336 3/20 0.32
DHODH Q02127 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7894085 0.90 PPOX (0.40) BCAT2BCAT1PPOX
SCHEMBL7894197 0.84 BCAT2 (0.33) BCAT2BCAT1
SCHEMBL7899859 0.84 PPOX (0.40) PPOXDHODH
SCHEMBL7901404 0.83 PPOX (0.39) PPOXDHODH
SCHEMBL7901376 0.82 PPOX (0.50) PPOXDHODH
SCHEMBL9049760 0.82 PPOX (0.34) BCAT2BCAT1PPOXDHODH
SCHEMBL9050670 0.81 PPOX (0.35) BCAT2BCAT1PPOXDHODH
SCHEMBL7899878 0.80 PPOX (0.38) PPOXDHODH
SCHEMBL7894182 0.78 LMNA (0.41) BCAT2BCAT1PPOX
SCHEMBL8137614 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US claimed
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US disclosed
EP-0902029-A1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-17 EP disclosed