SCHEMBL7901376

SCHEMBL7901376

CCOC(=O)C(C)Oc1cc(-n2c(=O)cc(C(F)(F)F)n3ccnc23)c(F)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPOX P50336 6/20 0.50
DHODH Q02127 10/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7899859 0.91 PPOX (0.40) PPOXDHODH
SCHEMBL7901404 0.91 PPOX (0.39) PPOXDHODH
SCHEMBL7894085 0.86 PPOX (0.40) PPOXMEN1KMT2A
SCHEMBL7901494 0.86 PPOX (0.50) PPOXMEN1KMT2A
SCHEMBL7901544 0.84 PPOX (0.33) PPOXDHODHMEN1KMT2A
SCHEMBL7894121 0.84 PPOX (0.35) PPOXMEN1KMT2A
SCHEMBL7901344 0.83 BAZ2B (0.39) PPOX
SCHEMBL7899181 0.82 BCAT2 (0.32) PPOXDHODH
SCHEMBL10574916 0.82 PPOX (0.55) PPOXDHODH
SCHEMBL7899878 0.82 PPOX (0.38) PPOXDHODHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US claimed
US-6191070-B1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-02-20 US disclosed
EP-0902029-A1 Pyrimidinone derivatives and herbicides containing them SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-03-17 EP disclosed