Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939326 | 0.82 | LSS (0.51) | MAPTLSSCHRNA7NPC1RAB9A | |
| SCHEMBL7900745 | 0.80 | KDM1A (0.46) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL14672093 | 0.80 | MAPT (0.57) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL9513813 | 0.77 | LMNA (0.78) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL17947648 | 0.77 | MAOA (0.50) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL7046801 | 0.77 | KDM1A (0.48) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL155771 | 0.77 | LMNA (0.78) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL10927812 | 0.76 | KDM1A (0.40) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL10928111 | 0.75 | CHRNA7 (0.40) | MAOAMAOBKDM1AMAPTLMNA | |
| SCHEMBL10322372 | 0.73 | CTSK (0.47) | MAOAMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191289-B1 | REACTING A 4-OXO-4H-BENZOPYRAN GROUP SUBSTITUTED WITH AMIDE OR A PHENYL GROUP IN ITS 2 POSITION IS REACTED WITH ANHYDROUS HYDRAZINE OR SALT IN PRESENCE OF CATALYST FOLLOWED BY REACTING WITH NITROUS ACID OR SALT TO FORM TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-02-20 | — | — | US | disclosed |