SCHEMBL7899371

SCHEMBL7899371

O=S(=O)(OCC(F)(F)C(F)(F)F)C(Cl)(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL55106 0.81 CA1 (0.52) CA1CA2CA9
SCHEMBL694351 0.81 CA2 (0.36) CA1CA2CA9
SCHEMBL777216 0.75 CA1 (0.44) CA1CA2CA9
SCHEMBL75966 0.74 CA2 (0.45) CA1CA2CA9
SCHEMBL8927969 0.74 CA1 (0.31) CA1CA2CA9
SCHEMBL11917853 0.72 CA1 (0.30) CA1CA2CA9
SCHEMBL777804 0.71 CA1 (0.52) CA1CA2CA9
SCHEMBL7257310 0.71 CA1 (0.36) CA1CA2CA9
SCHEMBL1981839 0.71 USP2 (0.40) CA1CA2CA9
SCHEMBL18632022 0.71 CA2 (0.36) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218364-B1 FOR THERAPY OF ASTHMA MERRELL PHARMACEUTICALS, INC. 2001-04-17 US disclosed