Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7899371 | 0.81 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL26912 | 0.79 | CA2 (0.56) | CA1CA2CA9HTT | |
| SCHEMBL8927969 | 0.78 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL14600039 | 0.76 | CA1 (0.33) | CA1CA2CA9 | |
| SCHEMBL11917853 | 0.76 | CA1 (0.30) | CA1CA2CA9 | |
| SCHEMBL775983 | 0.75 | CA1 (0.65) | CA1CA2CA9HTT | |
| SCHEMBL25850724 | 0.75 | CA1 (0.52) | CA1CA2CA9HTT | |
| SCHEMBL777502 | 0.75 | CA1 (0.52) | CA1CA2CA9HTT | |
| SCHEMBL972507 | 0.75 | CA1 (0.52) | CA1CA2CA9HTT | |
| SCHEMBL9321989 | 0.74 | CA1 (0.56) | CA1CA2CA9HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 413 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837364-A | REACTION OF HALOBENZENE WITH TRIFLUOROETHANOL | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-06-06 | — | — | US | claimed |
| EP-0197869-B1 | PROCESS FOR THE PREPARATION OF PENTAFLUOROETHOXY- AND PENTAFLUOROETHYL THIOBENZENE DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1989-05-31 | — | — | EP | claimed |
| EP-4076459-B1 | PRMT5 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2026-04-29 | — | — | EP | disclosed |
| US-12595248-B2 | PRMT5 inhibitors | MERCK SHARP & DOHME LLC (US) | 2026-04-07 | — | — | US | disclosed |
| US-20250100999-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2025-03-27 | — | — | US | disclosed |
| US-12122765-B2 | Methods and intermediates for preparing therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2024-10-22 | — | — | US | disclosed |
| US-12064429-B2 | Substituted 5-fluoro-1H-pyrazolopyridines and their use | ADVERIO PHARMA GMBH (DE) | 2024-08-20 | — | — | US | disclosed |
| EP-4403221-A2 | MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS | Gilead Sciences, Inc. (US) | 2024-07-24 | — | — | EP | disclosed |
| EP-2487161-B2 | Modulators of pharmacokinetic properties of therapeutics | GILEAD SCIENCES INC (US) | 2024-06-05 | — | — | EP | disclosed |
| US-20240101533-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | GILEAD SCIENCES, INC. | 2024-03-28 | — | — | US | disclosed |
| CN-114585628-B | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-0023422-A2 | Herbicidal sulfonamides, preparation and use thereof, and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-02-04 | — | — | EP | disclosed |
| US-4190666-A | ANTIARTHRITIC, ANALGESIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4182769-A | ANALGESIC, ANTIARTHRITIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-01-08 | — | — | US | disclosed |
| US-4169146-A | Novel morpholine derivatives and treating depression therewith | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1979-09-25 | — | — | US | disclosed |
| US-4159338-A | ANTIARTHRITIC, ANALGESIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4086236-A | ANTIBACTERIAL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-04-25 | — | — | US | disclosed |
| US-4085210-A | Novel morpholine derivatives and the treatment of mental depression | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-04-18 | — | — | US | disclosed |
| US-4036962-A | BACTERICIDES | E. I. DU PONT DE NEMOURS AND CO. (US) | 1977-07-19 | — | — | US | disclosed |
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12122765-B2 | Methods and intermediates for preparing therapeutic compounds | CYP11A1, CYP11B1, CYP11B2 | CA1 195/4885CA2 912/4885CA9 431/4885 |
| US-12064429-B2 | Substituted 5-fluoro-1H-pyrazolopyridines and their use | PFKP, PON1, FABP3 | CA1 4855/4885CA2 3900/4885CA9 4760/4885 |
| US-12595248-B2 | PRMT5 inhibitors | PRMT5, PRMT1, PRMT6 | CA1 3166/4885CA2 2138/4885CA9 3898/4885 |
| US-20240101533-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | CA1 195/4885CA2 912/4885CA9 431/4885 |
| US-20250100999-A1 | METHODS AND INTERMEDIATES FOR PREPARING THERAPEUTIC COMPOUNDS | CYP11A1, CYP11B1, CYP11B2 | CA1 195/4885CA2 912/4885CA9 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.