Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 11/20 | 0.45 |
| ▸ | CA1 | P00915 | 10/20 | 0.45 |
| ▸ | MMP1 | P03956 | 3/20 | 0.38 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 3/20 | 0.38 |
| ▸ | MMP8 | P22894 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1758440 | 0.92 | CA2 (0.45) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL286439 | 0.85 | CA2 (0.46) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL22117318 | 0.85 | CA2 (0.41) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL22117315 | 0.83 | CA2 (0.40) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL2359453 | 0.83 | CA2 (0.40) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL7755397 | 0.82 | CA2 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL22117313 | 0.82 | CA2 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL7750856 | 0.82 | CA2 (0.39) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL3027542 | 0.82 | CA2 (0.44) | CA2CA1MMP1MMP2MMP9 | |
| SCHEMBL15827020 | 0.82 | CA2 (0.44) | CA2CA1MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2024-05-28 | — | — | US | disclosed |
| US-20230087560-A1 | HYDROFLUORETHERS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY | 2023-03-23 | — | — | US | disclosed |
| EP-3623365-B1 | PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2023-01-04 | — | — | EP | disclosed |
| CN-113195674-A | Hydrofluoroolefins and methods of use thereof | 3M创新有限公司 | 2021-07-30 | — | — | CN | disclosed |
| WO-2021144678-A1 | HYDROFLUORETHERS AND METHODS OF USING SAME | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2021-07-22 | — | — | WO | disclosed |
| US-20200199096-A1 | PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-06-25 | — | — | US | disclosed |
| EP-3623365-A1 | PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT | Kumiai Chemical Industry Co., Ltd. (JP) | 2020-03-18 | — | — | EP | disclosed |
| US-8802713-B2 | 3-alkoxy-1-phenylpyrazole derivatives and pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2202226-B1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2013-06-05 | — | — | EP | disclosed |
| US-8261560-B2 | Methods of using hydrofluoroethers as heat transfer fluids | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-09-11 | — | — | US | disclosed |
| US-8129412-B2 | Hydantoin derivatives useful as metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2012-03-06 | — | — | US | disclosed |
| US-20110100601-A1 | METHODS OF USING HYDROFLUOROETHERS AS HEAT TRANSFER FLUIDS | 3M INNOVATIVE PROPERTIES COMPANY | 2011-05-05 | — | — | US | disclosed |
| US-20100210704-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVES AND PESTICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-2202226-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | Kumiai Chemical Industry CO., LTD. (JP) | 2010-06-30 | — | — | EP | disclosed |
| EP-1828166-B1 | HYDANTOIN DERIVATIVES USEFUL AS METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-07-22 | — | — | EP | disclosed |
| US-20080280950-A1 | Hydantoin Derivatives Useful as Metalloproteinase Inhibitors | ASTRAZENECA AB (SE) | 2008-11-13 | — | — | US | disclosed |
| EP-1828166-A1 | HYDANTOIN DERIVATIVES USEFUL AS METALLOPROTEINASE INHIBITORS | AstraZeneca AB (SE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006064218-A1 | HYDANTOIN DERIVATIVES USEFUL AS METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210704-A1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVES AND PESTICIDES | HCN3, HCN4, KCNH3 | CA2 609/4885CA1 2765/4885MMP1 279/4885 |
| US-20200199096-A1 | PYRAZOLE-3-CARBOXYLIC ACID AMIDE DERIVATIVE AND PEST CONTROL AGENT | H1-3, HDAC3, H1-0 | CA2 275/4885CA1 732/4885MMP1 4172/4885 |
| US-20230087560-A1 | HYDROFLUORETHERS AND METHODS OF USING SAME | NPFFR2, CYP2F1, CYP4F3 | CA2 345/4885CA1 1218/4885MMP1 4368/4885 |
| US-11993578-B2 | Pyrazole-3-carboxylic acid amide derivative and pest control agent | H1-3, HDAC3, H1-0 | CA2 275/4885CA1 732/4885MMP1 4172/4885 |
| US-20080280950-A1 | Hydantoin Derivatives Useful as Metalloproteinase Inhibitors | MMP3, MMP9, MMP2 | CA2 130/4885CA1 236/4885MMP1 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.