Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 12/20 | 0.43 |
| ▸ | MMP1 | P03956 | 8/20 | 0.43 |
| ▸ | MMP9 | P14780 | 8/20 | 0.43 |
| ▸ | MMP2 | P08253 | 7/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MMP16 | P51512 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7502927 | 0.89 | MMP13 (0.53) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7555235 | 0.87 | MMP13 (0.56) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7508946 | 0.85 | ALDH1A1 (0.45) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7516820 | 0.85 | MMP13 (0.54) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7901571 | 0.85 | MMP13 (0.59) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7898392 | 0.83 | MMP1 (0.42) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7509339 | 0.82 | MMP13 (0.61) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7509669 | 0.82 | MMP13 (0.41) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7513444 | 0.81 | MMP13 (0.41) | MMP13MMP1MMP9MMP2MMP3 | |
| SCHEMBL7903646 | 0.81 | MMP13 (0.41) | MMP13MMP1MMP9MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |