Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 10/20 | 0.59 |
| ▸ | MMP2 | P08253 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 4/20 | 0.49 |
| ▸ | MMP3 | P08254 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595438 | 0.92 | MMP13 (0.57) | MMP13MMP2KDM4EALDH1A1PKM | |
| SCHEMBL7509339 | 0.91 | MMP13 (0.61) | MMP13MMP2KDM4EALDH1A1PKM | |
| SCHEMBL7512022 | 0.89 | MMP2 (0.48) | MMP13MMP2KDM4EALDH1A1PKM | |
| SCHEMBL7510414 | 0.88 | MMP2 (0.56) | MMP13MMP2KDM4EALDH1A1KMT2A | |
| SCHEMBL7899733 | 0.85 | MMP13 (0.43) | MMP13MMP2KDM4EALDH1A1MMP1 | |
| SCHEMBL7508581 | 0.84 | MMP13 (0.53) | MMP13MMP2KDM4EALDH1A1PKM | |
| SCHEMBL7502927 | 0.84 | MMP13 (0.53) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7513672 | 0.83 | MMP13 (0.59) | MMP13MMP2KDM4EALDH1A1KMT2A | |
| SCHEMBL7555235 | 0.82 | MMP13 (0.56) | MMP13MMP2ALDH1A1MMP1MMP3 | |
| SCHEMBL7506693 | 0.80 | MMP2 (0.51) | MMP13MMP2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | claimed |
| US-6197770-B1 | ENZYME INHIBITORS; ANTIARTHRITIC AGENTS; BONE DISORDERS | THE PROCTER & GAMBLE CO. | 2001-03-06 | — | — | US | disclosed |