Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807478 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1GAAPKMLMNA | |
| SCHEMBL789748 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1GAACSNK1A1CLK4 | |
| SCHEMBL941858 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL29904585 | 0.77 | ALDH1A1 (1.00) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL24091986 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1GAAPKMLMNA | |
| SCHEMBL22521377 | 0.76 | KDM4E (0.57) | KDM4EALDH1A1GAACSNK1A1PKM | |
| SCHEMBL791113 | 0.73 | PRNP (0.48) | PIK3CGLMNACYP1A2MAPTTHRB | |
| SCHEMBL10813766 | 0.72 | ALDH1A1 (0.62) | KDM4EALDH1A1GAACSNK1A1CLK4 | |
| SCHEMBL9633299 | 0.71 | GPR35 (0.53) | KDM4EGPR35PSMB8PSMB5LMNA | |
| SCHEMBL23110066 | 0.71 | ACHE (0.45) | KDM4EPSMB8PSMB5PIK3CGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |