Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14900317 | 0.87 | MAPT (0.62) | HTR6MAPTGAAGLAHTT | |
| SCHEMBL7899993 | 0.84 | MAPT (0.56) | HTR6MAPTGAAGLAHTT | |
| SCHEMBL1274938 | 0.78 | HTT (0.73) | MAPTGAAHTTKMT2ALMNA | |
| SCHEMBL12260314 | 0.76 | MAPT (0.48) | HTR6MAPTGAAGLAHTT | |
| SCHEMBL7718950 | 0.76 | NPY1R (0.50) | MAPTGAAGLAHTTKMT2A | |
| SCHEMBL7718916 | 0.76 | NPY1R (0.50) | MAPTGAAGLAHTTKMT2A | |
| SCHEMBL7900009 | 0.75 | HTT (0.49) | MAPTGAAHTTKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL31232826 | 0.75 | HTR1A (0.57) | HTR6MAPTHTTKMT2ALMNA | |
| SCHEMBL6440712 | 0.74 | MAPT (0.60) | HTR6MAPTGAAGLAKMT2A | |
| SCHEMBL23536279 | 0.73 | HTR1A (0.58) | HTR6MAPTHTTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194399-B1 | E.G., N1-(2-AMINOETHYL)-4-NITRO-N3-(2-PHENOXYETHYL)-1,3-BENZENEDIAMINE AND N-(4-NITRO-N3-(4-(NITROPHENYL)-1-PIPERA-ZINYL)PHENYL)-1,2-ETHANEDIAMINE; BACTERICIDES; DRUG-RESISTANT -LOW RESISTANCE DEVELOPMENT; LOW HALF LIFE; BROAD SPECTRUM | SCRIPTGEN PHARMACEUTICALS, INC. | 2001-02-27 | — | — | US | disclosed |
| WO-2000021539-A1 | ARYLDIAMINE DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | ANADYS PHARMACEUTICALS, INC. (US) | 2000-04-20 | — | — | WO | disclosed |